This is a very rare complication, and is almost always associated with extensive ulceration of the primary growth or with an abscess in the peritoneum or one of the neighbouring organs. In the majority of cases it is characterised by an elevated irregular temperature, rapid emaciation, and intense anaemia; but occasionally abscesses form in the subcutaneous tissue, pus collects in the larger joints, or jaundice develops. In 2.3 per cent, of our cases ulcerative endocarditis of the aortic or mitral valves was discovered after death. In the case recorded by Hanot both the blood and the contents of the stomach contained streptococci.