A man, aged fifty-six, was admitted into hospital for anaemia. The history was very indefinite, but he had apparently been out of health for four months, and had become too weak to pursue his work as a general labourer. There was no complaint of pain or sickness, but he had become greatly emaciated and was very short of breath. On examination he presented profound anaemia, with oedema of the ankles and a pleuritic effusion on the left side. The spleen projected three inches below the costal margin, but the organ was not tender and its surface was quite smooth. The patient had never suffered from malaria. Just to the right of the navel was a round, movable, tender tumour about the size of a Tangerine orange, apparently connected with the stomach, which was somewhat dilated. The gastric contents were free from hydrochloric acid, and the blood contained a great excess of white corpuscles. On several occasions the patient vomited after dinner, but there was no haematemesis. Pain and swelling of the left leg developed, the temperature rose to 100° P., and the general debility increased. Death occurred from exhaustion within four weeks. A necropsy showed carcinoma of the pylorus with slight contraction of the orifice, a few secondary growths in the pancreas, and a large but apparently healthy spleen.