Cancer frequently develops upon the scars of various dermatoses. Most prominent of these is the scar resulting from ordinary burns of the third degree. Cancer originating in such lesions is commonly called Marjolin's ulcer. The first manifestation is almost invariably a superficial ulcer, with a considerable amount of rather foul discharge. A fungous overgrowth often results, with great induration around the edges. At other times there is simply a deep ulcer, accompanied by induration. Cancers of this type are usually of the spinous-celled variety, necessitating wide local removal, and enu- ^ cleation of the draining lymphatic glands. In severe cases situated upon the limbs amputation is usually necessary.