The problem of diagnosis is a threefold one. In the first place, it is necessary to consider the clinical aspect of the disease in its entirety, in order to establish the existence of certain general features, which may serve to distinguish it from other disorders of the digestive organs. In the second, the symptoms and signs which develop at an early period must be separated from those which mark an advanced stage of the complaint, so that a clue may be obtained to the recognition of a cancerous growth before it has progressed too far to admit of complete removal. Thirdly, those abnormal varieties of the complaint which have been previously described require to be differentiated from other diseases to which they bear a general resemblance.